Archive for Daybook
Next-Generation GigaHertz NMR
1 GHz NMR system with a first-generation, unshielded 23.5 Tesla magnet has been running at the Ultra-High Field NMR Center in Lyon, France since 2009. Bruker intends to deliver the world’s first, next-generation 1GHz NMR systems with actively-shielded Aeon™ 1 GHz magnets to the University of Bayreuth, Germany, in late 2015, and to the University of Toronto, Canada in the first half of 2016.
Ultra-high field NMR in combination with other experimental and computational methods, has recently been shown to enable more detailed studies of the structural ensembles, post-translational modifications, dynamics, multiple interactions, specific binding partners, signaling and regulatory roles, formation of membrane-less cellular organelles, and other functions of Intrinsically Disordered Proteins (IDPs).
From what we have already seen
Combined acquisition of NMR and UV-vis absorption spectra
Dr. Benjamin Koeppe (Humboldt-Universität zu Berlin, Germany), who previously worked in the group of Prof. Dr. Hans-Heinrich Limbach and developed a technique for the combined acquisition of NMR and UV-vis absorption spectra (UVNMR), is installing and demonstrating the equipment at the CMR. The figure shows NMR and UV-vis spectra of 2-chloro-4-nitrophenol dissolved in chloroform, obtained simultaneously within the magnet of an NMR spectrometer..
Our visitors
On April 24th 2015 Behruz Abtahi (representative of the Ministry of Science, Research and Technologies of Iran, Counsellor of the Embassy of the Iranian Republic), Mohammad Mehdi Tehranchi (Chancellor of Shahid Beheshti University, Tehran) and Kayvan Hosseini (Assistant professor at Allameh Tabatabai University, Tehran) have visited the center.
BioNMR
A postdoc in Prof. Dr. Nikolay R. Skrynnikov’s BioNMR laboratory, Kerstin Kampf, is researching temperature dependence of dynamics in intrinsically disordered proteins.
Bowling Green State University Visitors
Visitors from the University of Tokyo
Today prof. Kaoru Yamanouchi and prof. Kiichiro Hotayama from the University of Tokyo have visited the Center.