Center for Magnetic Resonance

1 GHz NMR system with a first-generation, unshielded 23.5 Tesla magnet has been running at the Ultra-High Field NMR Center in Lyon, France since 2009. Bruker intends to deliver the world’s first, next-generation 1GHz NMR systems with actively-shielded Aeon™ 1 GHz magnets to the University of Bayreuth, Germany, in late 2015, and to the University of Toronto, Canada in the first half of 2016.
Ultra-high field NMR in combination with other experimental and computational methods, has recently been shown to enable more detailed studies of the structural ensembles, post-translational modifications, dynamics, multiple interactions, specific binding partners, signaling and regulatory roles, formation of membrane-less cellular organelles, and other functions of Intrinsically Disordered Proteins (IDPs).

At CMR we have measured NMR spectra of these nuclei